NOT KNOWN FACTUAL STATEMENTS ABOUT BLOCK PAIN RECEPTORS WITH PROLEVIATE

The activation of CB1 and CB2 inhibits the formation of intracellular cAMP, as a result leading to a tremendous reduction of the excitatory outcome within the neurons [88,89]. Moreover, the activation of CB2 can even further reduce the mast mobile degranulation and the release of pro-inflammatory mediators, earning the reduction in pain sensation a